Twenty something woman in orange gym set making a heart shape over her tummy.

Intestinal permeability, the gut–immune axis, and allergic disease: Clinical implications for practice

Allergic diseases are traditionally framed as disorders of inappropriate immune reactivity to environmental antigens such as pollen, foods, or house dust mite. However, a growing body of evidence suggests that gastrointestinal barrier integrity and gut microbial ecology play a central role in shaping allergic susceptibility and symptom expression.

Given that approximately 70–80% of immune tissue resides within the gut‑associated lymphoid tissue (GALT), even subtle disturbances in intestinal permeability or microbiota composition may influence immune tolerance and inflammatory tone far beyond the gastrointestinal tract (Wiertsema, 2021).

In this blog, nutritional therapist Ruth explores the mechanistic links between intestinal permeability (“leaky gut”) and allergic disease, with particular reference to allergic rhinitis, but also within the broader context of atopy.

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Last updated on 19th February 2026 by cytoffice

How to use multivitamins in clinical practice

In modern clinical practice, multivitamins have evolved far beyond the generic “nutritional safety net” they were once perceived to be. As our understanding of personalised nutrition deepens, it’s increasingly clear that foundational micronutrient support can play a pivotal therapeutic role, whether addressing nutrient gaps, supporting complex biochemical pathways such as methylation and detoxification, or meeting the heightened physiological demands of specific life stages. For practitioners, using multivitamins effectively means selecting targeted, bio‑effective formulations that align with an individual’s unique health profile, ensuring they deliver meaningful clinical impact rather than superficial coverage.

In this blog, our nutritional therapist, Ruth, takes a deep dive into how to select, and then effectively use multivitamin supplements in your practice, focusing on specific population groups and their individual needs.

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Last updated on 10th February 2026 by cytoffice

Close up macro shot of a of green lettuce leaf. Eating a nutrient-rich, anti-inflammatory diet rich in an abundnace of fruits and vegetables is essential for optimal methylation.

Why methylation matters – the complex process at the heart of human health

A complex topic that can be baffling and spark differing opinions, methylation is critical to health as it’s at the heart of so many of our body’s key processes. Annie Edwards demystifies methylation and explains how you can use it to support the health of your clients.

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Last updated on 4th February 2026 by cytoffice

GLP agonies – Supporting clients on GLP medications

Use of GLP-1 medications for weight loss is accelerating rapidly with Mounjaro & Wegovy now household names. Are these drugs a panacea for the obesity epidemic, or do the wide-ranging side effects make them a healthcare time bomb? Let’s take a close look at the ‘GLP-1 receptor agonists’ – how they work, what the side effects are, and how we can help, as well as natural alternatives.

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Last updated on 12th January 2026 by cytoffice

Self-defence – Supplements for immunity and lung function

Since the pandemic, our awareness, perhaps even fear, of viral and other infections has increased. But we have always existed in a world where we might encounter evolving variants of viral infection, with some of us seemingly more susceptible or even vulnerable than others due to our general health.

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Last updated on 10th December 2025 by cytoffice

Abstract of woman sat cross legged on the floor at yoga practicing a breathing exercise to keep her lungs healthy. Her right hand is on her chest and her left hand is on her belly.

Seeking inspiration – looking after the lungs

To breathe is to live.  Although we have a regular need for food to provide energy for life, the body has a more essential, immediate and continuous requirement for oxygen, which is fundamental to energy metabolism and cell survival.  Oxygen is chemically indispensable, and the rhythmic, largely unconscious, act of breathing that draws it in not only sustains life but also represents life’s rhythm and contributes to emotional balance.

In this week’s blog, our expert Nutritional Therapist, Annie, looks at how you can you keep your lungs healthy.

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Last updated on 2nd December 2025 by cytoffice